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????, 2025? 9? 24? /PRNewswire/ -- ?? ??? ??(CVD)?? ?? ????? ? 1,800? ?? ???, ?? ?? ??? ?? ??? ?? ?? ??? ??. ???? ????, ????? ? ???? ?? ??? ?? ???? ?? Lp(a)? ??? ??.1,2 Lp(a)? "??? ???? a"? ???, ? ?? ??? 5? ? 1??? ??? ??? ??? ??? ??. ??, Lp(a) ???? ?? ???4, ??? ?? ??? ?? ?? ????? ?? ???? ??.3
?? ??? ?(9? 29?)? ???, Global Heart Hub? ????? ?? ?? ????? ?? "??? ???? (a)? ???"?? ???? ??? ???? ????. ? ?????? Lp(a) ??? ???? ?? ??? ?? ??? ?? ????? ????? ???, ????? ? ???? ?? ??? ???? ?? ????.5,6
???????? ?? ???? ??? ???, ??? ??? ? ?? ???? ??? 3? ? 2?(66%)? ????? ?? ??? ?? ???, ??(45%)? ???? ?? ??? ?? ??? ???? ??? ?? ??? ????. Lp(a)? ?? ??? ?? ? ??, ???? 22%?? ????? ??? ?? ??? ?? ???, ? ? 7%?? ????? ??? ???? ????.7
Global Heart Hub? Neil Johnson ????? "??? ??? ??? ? ????? ?? ?? ?????, ?? ?? ?? ??? ?? Lp(a)? ??? ???? ??? ??"? "??? ??? ????, ???? ???? ?? ? ?? ??? ? ?? ?? ?? ?? ??? ??? ??? ?? ? ??? ??? ??? ???"? ???.
???? ????: ??? ?? ??
? ???? ?? ?? ??, ?? ???, ???? ?? ??? ?? ???? ????.
??? ??? ? ?? ???? ????? Lp(a) ??? ?? ?? ??? ?? ?????, 58%? ??? ??? ????? ??? ???? ?? ????? ??? ?? ? ?? ??? ??? ? ?? ??? ??? ????.7
???? ??? ??? ? ?? ???? Lp(a) ?? ??? ???? ?? ??? ?? Lp(a) ??? ?? ? ??? ?? ???? ????? ?? ??? ??? ???? ??? ???? ?????.
????? Judith Love ??, ?? ? ???? ?? ?? ??? "?? ? ?? ???? ? ??? ??? ?? ? ???, ??? ???? ??? ?? ? ??"?, "??? ?? ? ?? ???? ???? '??? ???? (a)'? ?? ??? ???? ?? ??? ????, ???? ???? ?? ?? ??? ?? ??? ?? ? ??? ????"? ???.
??? ????
Lp(a) ??
Lp(a)? ??? ???(LDL)? ????? ??? ??? ????? ?????(a) ??? ???? ??? ??? ??? ??.8 ? ?? ???? Lp(a)? ?? '???' ??? ???, ?? ? ??? ??? ??? ? ??.9
Lp(a) ?? ??? ?????? ?? ? ??? ??? ???? ????, ?? ?? ?? ??? ???? ???? ?? ???? ?? ? ?? ??? ????. ?? ?? ?? ?? ??? ?? ? ??. ??? ??? ??? ???? ????, ???? ?? ?? ???? ?? ??? ??? ??? ? ??.10
Lp(a) ??? ????? ? 90% ????, ?? 5? ?? ????, ?? ??? ???? ????.11,12 ???, ???? ? ??? ?? ???? ??? Lp(a) ??? ??? ??? ?? ??.
Global Heart Hub ??
Global Heart Hub(GHH)? ??? ??? ?? ??? ?? ???? ?? ?? ??? ??? ??? ??? ????. GHH? 150? ??? ?? ?? ??? ???? ? ?? ?? ??? ???? ?? ??? ??. GHH? ??? ? ?? ?? ??? ??? ???? ?? ??? ?? ???? ?? ?? ???? ?? ???? ?? ??? ???? ???. GHH? ?? ?? ???? ??? ????, ??? ?? ???? ??? ??, ??? ?? ??? ????, ??? ??? ? ?? ?????. GHH? ??? ?? ??? ?? ??? ??? ????, ?? ??? ????, ?? ?? ????, ??? ??? ??? ????? ?? ??? ?? ??.
???? ??
????? ???? ??????, ???? ?? ???? ??? ???? ?? ??? ????? ?? ?? ???? ??? ??? ??? ?? ??, ?? ??? ? ??? ??? ????? ????. ????? ???? ? ?? 2? 5?? ? ???? ???? ??.
???? ?? ??? ???:? ??????.
????
[1] World Health Organization. (n.d.). Cardiovascular diseases. World Health Organization. Accessed Aug 22, 2025, from
[2] World Health Organization. (2024, February 1). Global cancer burden growing, amidst mounting need for services. World Health Organization. Accessed Aug 22, 2025, from
[3] Tsimikas S, Marcovina SM. J Am Coll Cardiol. 2022;80(9):934–946
[4] Kronenberg F, et al. The Brussels International Declaration on Lp(a) Testing and Management. Atherosclerosis. 2025. doi:10.1016/S0021-9150(25)00116-9
[5] Kronenberg F et al. Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement. Eur Heart J. 2022 Oct 14;43(39):3925-3946
[6] Vinci P et al. Lipoprotein(a) as a Risk Factor for Cardiovascular Diseases: Pathophysiology and Treatment Perspectives. Int J Environ Res Public Health. 2023 Sep 6;20(18):6721
[7] Novartis-commissioned online survey, March 17–30, 2025; adults 21–75 in Australia, India, South Korea, Taiwan Region, Saudi Arabia, and the UAE (n=1,800; n=300/market); nationally representative by age and gender. Data on file.
[8] Schmidt K, Noureen A, Kronenberg F, Utermann G. Structure, function, and genetics of lipoprotein (a). J Lipid Res. 2016;57(8):1339-1359. doi:10.1194/jlr.R067314.
[9] Cox RA, Garcia-Palmieri MR. Cholesterol, triglycerides, and associated lipoproteins. In: Walker HK, Hall WD, Hurst JW, editors. Clinical Methods: The History, Physical, and Laboratory
[10] American Heart Association. Lipoprotein (a) Meaning and How Does it Impact My Heart Health? [Internet]. American Heart Association; [cited 2025 May 26 2025]. Available from:
[11] Tsimikas S. A test in context: lipoprotein(a): diagnosis, prognosis, controversies, and emerging therapies. J Am Coll Cardiol. 2017;69(6):692-711.
[12] Wilson, D. P., Jacobson, T. A., Jones, P. H., Koschinsky, M. L., McNeal, C. J., Nordestgaard, B. G., & Orringer, C. E. (2019). Use of Lipoprotein(a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association. Journal of clinical lipidology, 13(3), 374–392.